Buffalo Bills' offensive success: How they dominated the 49ers + Matt Milano’s return & more!

BUFFALO, N.Y. — While the lake effect storm over the weekend wasn't the worst inch, or 18, that Buffalo has ever seen, it was ...

BUFFALO, N.Y. — Buffalo Police are investigating an incident that occurred at a neighborhood favorite: Gene McCarthy's Old ...

Buffalo mayoral candidate Garnell Whitfield sits down to talk about bringing change, addressing housing issues, and ...

The U.S. government has closed its investigation into the outbreak tied to slivered onions in Quarter Pounders.

LOCKPORT, N.Y. — New York State Police shared on Tuesday troopers in Lockport arrested four teens after a stolen vehicle ...

The city's financial overseer produces the report annually to provide a "snapshot" of trends over the past 5 years and inform ...

The fire early Monday morning caused millions of dollars in damages, but luckily no employees or cows were hurt.

In addition to providing holiday entertainment, EverHaunt is also focusing on giving back to the community during the season ...

TONAWANDA, N.Y. — On Tuesday, hundreds of former Sumitomo Rubber Plant employees met with potential employers at a big job ...

With approximately 4,000 active volunteers working around the clock, the FeedMore warehouse is a bustling hub of activity.

President and CEO of Buffalo Museum of Science Gary Siddall and Dr. Holly Schreiber joined Most Buffalo in studio Tuesday to ...