Colin Cowherd believes that the Buffalo Bills are the best team in the NFL when playing at full strength. Somebody forgot to ...

San Francisco 49ers quarterback Brock Purdy missed last week's game against the Green Bay Packers. Will he play against the ...

Former Buffalo Bills quarterback Ryan Fitzpatrick recently sang the praises of current field general Josh Allen.

Bills: The Buffalo Bills were off in Week 12, so they didn’t move in our rankings. They are still the clear No. 2 team in the ...

Before you make any Week 13 NFL picks, be sure to see the exact NFL score predictions from SportsLine expert Eric Cohen.

Not interested in this game? Check out expert picks and best bets for every NFL game this week. Buffalo had its bye and the ...

The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

Buffalo Bills coach Sean McDermott looked and sounded refreshed as he and his team returned from its bye week.

Former Buffalo Bills wide receiver Stefon Diggs was reportedly "detrimental" to the atmosphere of the team as well as ...

Three teams face playoff-clinching scenarios in Week 13. Here's what the Bills, Lions and Chiefs need to earn a playoff berth ...

It’s Week 13 in the NFL, and the Buffalo Bills are preparing to host the San Francisco 49ers on Sunday Night Football at 8:20 ...

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...