During the Pittsburgh Steelers’ 20-10 win over the Los Angeles Chargers on Sunday, Jaylen Warren exited the game early. What’s the latest on Warren’s status, and will he be available in Week 4 when the Steelers face the Indianapolis Colts?

When RB Jaylen Warren and the Pittsburgh Steelers square off with the Indianapolis Colts in Week 4 on Sunday at 1:00 PM ET, they will be going up against the Colts' 31st-ranked run defense, which is giving up 179 rushing yards per game.

The Steelers will be without Jaylen Warren against the Indianapolis Colts as the running back recovers from a knee injury that occured in the Week 3 win against the Los Angeles Chargers. Warren didn't participate in practice all week and was ruled out Friday.

The Pittsburgh Steelers will be without running back Jaylen Warren (knee) and three others in their attempt to remain undefeated versus the Indianapolis Colts on Sunday. Here’s a look at the full injury report for the Steelers and Colts following Friday’s practice:

Steelers head coach Mike Tomlin did not rule out running back Jaylen Warren for Week 4 during his Tuesday press conference, but it sounds like he’s unlikely to play.

It appears increasingly likely that the Pittsburgh Steelers will be without running back Jaylen Warren for their next game, and that left guard Isaac Seumalo also might not return to the lineup. Warren missed a second consecutive day of practice Thursday,

The Pittsburgh Steelers are heading back on the road this week for a showdown with the Indianapolis Colts. Unfortunately, despite their 3-0 start, the injuries are starting to pile up, which could make their Week 4 outing more of an uphill battle than it needs to be against a dysfunctional Colts offense.

As expected throughout the week, Friday’s league-mandated Pittsburgh Steelers status report made official that running back Jaylen Warren, outside linebacker Alex Highsmith and reserve tight end MyCole Pruitt will not play in Sunday’s game at the Indianapolis Colts.